Highest cholesterol level was measured in groups administered with norfloxacin (164.17± 3.55), followed by control (163.36☑.99), ciprofloxacin (161.53☓.14) and enrofloxacin (160.78± 3.18). Highest blood glucose level was measured for control (239.21 ± 5.26), followed by groups treated with enrofloxacin (233.54± 4.19), ciprofloxacin (227.76 ±4.71) and lowest in norfloxacin (225.47 ± 4.85). Blood was collected directly from wing vein and serum was analyzed for estimation of blood proteins, glucose level, cholesterol and albumin which showed non-significant (P>0.05) response to quinolones treatment. Three commonly used quinolones including enrofloxacin, ciprofloxacin and norfloxacin were used for four weeks with one week of adaptation period, while, one group served as negative control. For this purpose, a total of 48 laying hens were selected and allocated into four groups, each group included three replicates containing four birds in each. Asif ur Rehman1, Arsalan Khan2*, Sarzamin Khan1, Hamza Maris3, Naseer Khan4 1Department of Poultry Science, Faculty of Animal Husbandry and Veterinary Sciences, Agriculture University Peshawar, 25000, Pakistan 2Livestock Research and Development Station, Paharpur, Dera Ismail Khan-29050-Pakistan 3Department of Poultry and Animal Sciences, Faculty of Veterinary and Animal Sciences, Gomal University, Dera Ismail Khan-29050-Pakistan 4Livestock and Dairy Development Department (Extension), Khyber Pakhtunkhwa Peshawar-25000-PakistanĪbstract | A study was designed to investigate the effects of quinolones antibiotics on the blood profile, blood glucose level, histomorphological features of pancreas and egg production of laying hens.
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